PRODUÇÃO CIENTÍFICA

1: Theofilas P, Ehrenberg AJ, Nguy A, Thackrey JM, Dunlop S, Mejia MB, Alho AT, Paraizo Leite RE, Rodriguez RD, Suemoto CK, Nascimento CF, Chin M, Medina-Cleghorn D, Cuervo AM, Arkin M, Seeley WW, Miller BL, Nitrini R, Pasqualucci CA, Filho WJ, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer’s disease Braak stages: a quantitative study in humans. Neurobiol Aging. 2018 Jan;61:1-12. doi: 10.1016/j.neurobiolaging.2017.09.007. Epub 2017 Sep 20.

2: Nunes PV, Suemoto CK, Leite RE, Ferretti-Rebustini RE, Pasqualucci CA, Nitrini R, Farfel JM, de Oliveira KC, Grinberg LT, da Costa NR, Nascimento CF, Salmasi F, Kim HK, Young LT, Jacob-Filho W, Lafer B. Factors associated with brain volume in major depression in older adults without dementia: results from a large autopsy study. Int J Geriatr Psychiatry. 2018 Jan;33(1):14-20. doi: 10.1002/gps.4649. Epub 2017 Jan 5.

3: Eser RA, Ehrenberg AJ, Petersen C, Dunlop S, Mejia MB, Suemoto CK, Walsh CM, Rajana H, Oh J, Theofilas P, Seeley WW, Miller BL, Neylan TC, Heinsen H, Grinberg LT. Selective Vulnerability of Brainstem Nuclei in Distinct Tauopathies: A Postmortem Study. J Neuropathol Exp Neurol. 2018 Feb 1;77(2):149-161. doi: 10.1093/jnen/nlx113.

4: Suemoto CK, Grinberg LT, Leite REP, Ferretti-Rebustini REL, Jacob-Filho W, Yaffe K, Nitrini R, Pasqualucci CA. Morphometric measurements of extracranial and intracranial atherosclerotic disease: A population-based autopsy study. Atherosclerosis. 2018 Mar;270:218-223. doi: 10.1016/j.atherosclerosis.2017.12.015. Epub 2017 Dec 9.

5: Nascimento C, Di Lorenzo Alho AT, Bazan Conceição Amaral C, Leite REP, Nitrini R, Jacob-Filho W, Pasqualucci CA, Hokkanen SRK, Hunter S, Keage H, Kovacs GG, Grinberg LT, Suemoto CK. Prevalence of transactive response DNA-binding protein 43 (TDP-43) proteinopathy in cognitively normal older adults: systematic review and meta-analysis. Neuropathol Appl Neurobiol. 2018 Apr;44(3):286-297. doi: 10.1111/nan.12430. Epub 2017 Sep 20.

1: Alegro M, Theofilas P, Nguy A, Castruita PA, Seeley W, Heinsen H, Ushizima DM, Grinberg LT. Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding. J Neurosci Methods. 2017 Apr 15; 282:20-33. PMID: 28267565. PMCID: PMC5600818

2: Alho ATDL, Hamani C, Alho EJL, da Silva RE, Santos GAB, Neves RC, Carreira LL, Araújo CMM, Magalhães G, Coelho DB, Alegro MC, Martin MGM, Grinberg LT, Pasqualucci CA, Heinsen H, Fonoff ET, Amaro E. Magnetic resonance diffusion tensor imaging for the pedunculopontine nucleus: proof of concept and histological correlation. Brain Struct Funct. 2017 Aug; 222(6):2547-2558. PMID: 28283747. PMCID: PMC5610900

3: Ehrenberg AJ, Nguy AK, Theofilas P, Dunlop S, Suemoto CK, Di Lorenzo Alho AT, Leite RP, Diehl Rodriguez R, Mejia MB, Rüb U, Farfel JM, de Lucena Ferretti-Rebustini RE, Nascimento CF, Nitrini R, Pasquallucci CA, Jacob-Filho W, Miller B, Seeley WW, Heinsen H, Grinberg LT. Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer’s disease. Neuropathol Appl Neurobiol. 2017 Jan 24. PMID: 28117917.

4: Grinberg LT, Heinsen H.. Light at the beginning of the tunnel? Investigating early mechanistic changes in Alzheimer’s disease. Brain. 2017 Nov 1;140(11):2770-2773. PMID: 29088348.

5: Nascimento C, Di Lorenzo Alho AT, Bazan Conceição Amaral C, Leite REP, Nitrini R, Jacob-Filho W, Pasqualucci CA, Hokkanen SRK, Hunter S, Keage H, Kovacs GG, Grinberg LT, Suemoto CK. Prevalence of transactive response DNA-binding protein 43 (TDP-43) proteinopathy in cognitively normal older adults: systematic review and meta-analysis. Neuropathol Appl Neurobiol. 2017 Aug 09. PMID: 28793370.

6: Suemoto CK, Ferretti-Rebustini RE, Rodriguez RD, Leite RE, Soterio L, Brucki SM, Spera RR, Cippiciani TM, Farfel JM, Chiavegatto Filho A, Naslavsky MS, Zatz M, Pasqualucci CA, Jacob-Filho W, Nitrini R, Grinberg LT. Neuropathological diagnoses and clinical correlates in older adults in Brazil: A cross-sectional study. PLoS Med. 2017 Mar; 14(3):e1002267. PMID: 28350821. PMCID: PMC5369698.

7: Dos Santos Matioli MNP, Suemoto CK, Rodriguez RD, Farias DS, da Silva MM, Leite REP, Ferretti-Rebustini REL, Farfel JM, Pasqualucci CA, Jacob Filho W, Arvanitakis Z, Naslavsky MS, Zatz M, Grinberg LT, Nitrini R. Diabetes is Not Associated with Alzheimer’s Disease Neuropathology. J Alzheimers Dis. 2017;60(3):1035-1043. doi: 10.3233/JAD-170179.

8: Theofilas P, Ehrenberg AJ, Dunlop S, Di Lorenzo Alho AT, Nguy A, Leite REP, Rodriguez RD, Mejia MB, Suemoto CK, Ferretti-Rebustini REL, Polichiso L, Nascimento CF, Seeley WW, Nitrini R, Pasqualucci CA, Jacob Filho W, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. Locus coeruleus volume and cell population changes during Alzheimer’s disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery. Alzheimers Dement. 2017 Mar;13(3):236-246. doi: 10.1016/j.jalz.2016.06.2362. Epub 2016 Aug 8.

9: Matioli MNPDS, Suemoto CK, Rodriguez RD, Farias DS, da Silva MM, Leite REP, Ferretti-Rebustini REL, Pasqualucci CA, Jacob W Filho, Grinberg LT, Nitrini R. Association between diabetes and causes of dementia: Evidence from a clinicopathological study. Dement Neuropsychol. 2017 Oct-Dec;11(4):406-412. doi: 10.1590/1980-57642016dn11-040010..

10: Nishizawa A, Suemoto CK, Farias-Itao DS, Campos FM, Silva KCS, Bittencourt MS, Grinberg LT, Leite REP, Ferretti-Rebustini REL, Farfel JM, Jacob-Filho W, Pasqualucci CA. Morphometric measurements of systemic atherosclerosis and visceral fat: Evidence from an autopsy study. PLoS One. 2017 Oct 16;12(10):e0186630. doi: 10.1371/journal.pone.0186630. eCollection 2017.

1: Farias-Itao DS, Pasqualucci CA, Nishizawa A, Silva LF, Campos FM, Silva KC, Leite RE, Grinberg LT, Ferretti-Rebustini RE, Jacob Filho W, Suemoto CK. Perivascular Adipose Tissue Inflammation and Coronary Artery Disease: An Autopsy Study Protocol. JMIR Res Protoc. 2016 Nov 18; 5(4):e211. PMID: 27864166. PMCID: PMC5135732.

2: Grinberg LT, Anghinah R, Nascimento CF, Amaro E, Leite RP, Martin MD, Naslavsky MS, Takada LT, Filho WJ, Pasqualucci CA, Nitrini R. Chronic Traumatic Encephalopathy Presenting as Alzheimer’s Disease in a Retired Soccer Player. J Alzheimers Dis. 2016 Jul 29; 54(1):169-174. PMID: 27472879.

3: Grothe MJ, Heinsen H, Amaro E, Grinberg LT, Teipel SJ. Cognitive Correlates of Basal Forebrain Atrophy and Associated Cortical Hypometabolism in Mild Cognitive Impairment. Cereb Cortex. 2016 Jun;26(6):2411-26. PMID: 25840425.

4: Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR,Munoz DG, Murray ME, Nelson PT, Takahashi H, Trojanowski JQ, Ansorge O, Arzberger T, Baborie A, Beach TG, Bieniek KF, Bigio EH, Bodi I, Dugger BN, Feany M, GelpiE, Gentleman SM, Giaccone G, Hatanpaa KJ, Heale R, Hof PR, Hofer M, Hortobágyi T, Jellinger K, Jicha GA, Ince P, Kofler J, Kövari E, Kril JJ, Mann DM, Matej R,McKee AC, McLean C, Milenkovic I, Montine TJ, Murayama S, Lee EB, Rahimi J, Rodriguez RD, Rozemüller A, Schneider JA, Schultz C, Seeley W, Seilhean D, Smith C, Tagliavini F, Takao M, Thal DR, Toledo JB, Tolnay M, Troncoso JC, Vinters HV, Weis S, Wharton SB, White CL 3rd, Wisniewski T, Woulfe JM, Yamada M, Dickson DW.Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathol. 2016 Jan;131(1):87-102. doi: 10.1007/s00401-015-1509-x. Epub 2015 Dec 10. PubMed PMID: 26659578.

5: Leite RE, Grinberg LT. Closing the gap between brain banks and proteomics to advance the study of neurodegenerative diseases. Proteomics Clin Appl. 2015 Oct;9(9-10):832-7. PMID: 26059592.

6: McAleese KE, Alafuzoff I, Charidimou A, De Reuck J, Grinberg LT, Hainsworth AH, Hortobagyi T, Ince P, Jellinger K, Gao J, Kalaria RN, Kovacs GG, Kövari E, Love S, Popovic M, Skrobot O, Taipa R, Thal DR, Werring D, Wharton SB, Attems J. Post-mortem assessment in vascular dementia: advances and aspirations. BMC Med. 2016; 14(1):129. PMID: 27600683.

7: Miller ZA, Sturm VE, Camsari GB, Karydas A, Yokoyama JS, Grinberg LT, Boxer AL, Rosen HJ, Rankin KP, Gorno-Tempini ML, Coppola G, Geschwind DH, Rademakers R, Seeley WW, Graff-Radford NR, Miller BL. Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture. Neurol Neuroimmunol Neuroinflamm. 2016 Dec; 3(6):e301. PMID: 27844039. PMCID: PMC5087253.

8: Nascimento C, Suemoto CK, Rodriguez RD, Alho AT, Leite RP, Farfel JM, Pasqualucci CA, Jacob-Filho W, Grinberg LT. Higher prevalence of TDP-43 proteinopathy in cognitively normal asians: A clinicopathological study on a multiethnic sample. Brain Pathol. 2016 Mar;26(2):177-85. PMID: 26260327.

9: Nishizawa A, Suemoto CK, Farias DS, Campos FM, da Silva KC, Cuelho A, Leite RE, Ferretti-Rebustini RE, Grinberg LT, Farfel JM, Jacob-Filho W, Pasqualucci CA. Association between adiposity and systemic atherosclerosis: a protocol of a cross-sectional autopsy study. Open Heart. 2016; 3(2):e000433. PMID: 27621828.

10: Rodriguez RD, Suemoto CK, Molina M, Nascimento CF, Leite RE, de Lucena Ferretti-Rebustini RE, Farfel JM, Heinsen H, Nitrini R, Ueda K, Pasqualucci CA, Jacob-Filho W, Yaffe K, Grinberg LT. Argyrophilic Grain Disease: Demographics, Clinical, and Neuropathological Features From a Large Autopsy Study. J Neuropathol Exp Neurol. 2016 Jul; 75(7):628-35. PMID: 27283329.

11: Stratmann K, Heinsen H, Korf HW, Del Turco D, Ghebremedhin E, Seidel K, Bouzrou M, Grinberg LT, Bohl J, Wharton SB, den Dunnen W, Rüb U. Precortical phase of Alzheimer’s disease (AD)-related tau cytoskeletal pathology. Brain Pathol. 2016 May;26(3):371-86. PMID: 26193084.

12: Takada LT, Bahia VS, Guimarães HC, Costa TV, Vale TC, Rodriguez RD, Porto FH, Machado JC, Beato RG, Cesar KG, Smid J, Nascimento CF, Grinberg LT, Brucki SM, Maximino JR, Camargos ST, Chadi G, Caramelli P, Nitrini R. GRN and MAPT Mutations in 2 Frontotemporal Dementia Research Centers in Brazil. Alzheimer Dis Assoc Disord. 2016 Apr 14. PMID: 27082848.

13: Theofilas P, Dunlop S, Heinsen H, Grinberg LT. Turning on the Light Within: Subcortical Nuclei of the Isodentritic Core and their Role in Alzheimer’s Disease Pathogenesis. J Alzheimers Dis. 2015 May 7; 46(1):17-34. PMID: 25720408.

14: Villela D, Ramalho RF, Silva AR, Brentani H, Suemoto CK, Pasqualucci CA, Grinberg LT, Krepischi AC, Rosenberg C. Differential DNA Methylation of MicroRNA Genes in Temporal Cortex from Alzheimer’s Disease Individuals. Neural Plast. 2016; 2016:2584940. PMID: 27213057.

15: Villela D, Suemoto CK, Pasqualucci CA, Grinberg LT, Rosenberg C. Do Copy Number Changes in CACNA2D2, CACNA2D3, and CACNA1D Constitute a Predisposing Risk Factor for Alzheimer’s Disease? Front Genet. 2016; 7:107. PMID: 27379157.

16: Di Lorenzo Alho AT, Suemoto CK, Polichiso L, Tampellini E, de Oliveira KC, Molina M, Santos GA, Nascimento C, Leite RE, de Lucena Ferreti-Rebustini RE, da Silva AV, Nitrini R, Pasqualucci CA, Jacob-Filho W, Heinsen H, Grinberg LT. Three-dimensional and stereological characterization of the human substantia nigra during aging. Brain Struct Funct. 2016 Sep;221(7):3393-403. doi: 10.1007/s00429-015-1108-6. Epub 2015 Sep 19.

17: Di Lorenzo Alho AT, Suemoto CK, Polichiso L, Tampellini E, de Oliveira KC, Molina M, Santos GA, Nascimento C, Leite RE, de Lucena Ferreti-Rebustini RE, da Silva AV, Nitrini R, Pasqualucci CA, Jacob-Filho W, Heinsen H, Grinberg LT. Three-dimensional and stereological characterization of the human substantia nigra during aging. Brain Struct Funct. 2016 Sep;221(7):3393-403. doi: 10.1007/s00429-015-1108-6. Epub 2015 Sep 19.

1: Di Lorenzo Alho AT, Suemoto CK, Polichiso L, Tampellini E, de Oliveira KC, Molina M, Santos GA, Nascimento C, Leite RE, de Lucena Ferreti-Rebustini RE, da Silva AV, Nitrini R, Pasqualucci CA, Jacob-Filho W, Heinsen H, Grinberg LT. Three-dimensional and stereological characterization of the human substantia nigra during aging. Brain Struct Funct. 2015 Sep 19. [Epub ahead of print]

2: Ferretti-Rebustini REL, Jacob-Filho W, Suemoto CK, Farfel JM, Leite REP, Grinberg LT, et al. Factors associated with morphometric brain changes in cognitively normal aging. Dement. Neuropsychol. 2015;9(2):103-109

3: Gardner RC, Possin KL, Hess CP, Huang EJ, Grinberg LT, Nolan AL, Cohn-Sheehy BI, Ghosh PM, Lanata S, Merrilees J, Kramer JH, Berger MS, Miller BL, Yaffe K, Rabinovici GD. Evaluating and treating neurobehavioral symptoms in professional American football players: Lessons from a case series. Neurol Clin Pract. 2015 Aug;5(4):285-295.

4: Grinberg LT, Jimenez CR, Li KW. Neuroproteomics: Applications in Neuroscience and Neurology. Biochim Biophys Acta. 2015 Jul; 1854(7):703-704. PMID: 25858468

5: Grothe MJ, Heinsen H, Amaro E, Grinberg LT, Teipel SJ. Cognitive Correlates of Basal Forebrain Atrophy and Associated Cortical Hypometabolism in Mild Cognitive Impairment. Cereb Cortex. 2015 Apr 2 [Epub ahead of print]. PMID: 25840425

6: Leite REP, Grinberg LT. Closing the gap between brain banks and proteomics to advance the study of neurodegenerative diseases. PROTEOMICS-Clinical Applications 2015 Jun 1 [Epub ahead of print]. PMID: 2588468

7: Madeira C, Lourenco MV, Vargas-Lopes C, Suemoto CK, Brandão CO, Reis T, Leite RE, Laks J, Jacob-Filho W, Pasqualucci CA, Grinberg LT, Ferreira ST, Panizzutti R. d-serine levels in Alzheimer’s disease: implications for novel biomarker development. Transl Psychiatry. 2015; 5:e561. PMID: 25942042.

8: Magraoui FE, Schrötter A, Heinsen H, Leite R, Park YM, Meyer HE, Grinberg LT. A Long Journey from Childhood to Senility: The 23rd HUPO BPP Workshop: 16-17 April 2015, São Paulo, Brazil. Proteomics. 2015 Sep;15(17):2895-7.

9: Molina M, Steinbach S, Park YM, Yun SY, Di Lorenzo Alho T, Heinsen H, Grinberg LT, Marcus K, Leite RE, May C. Enrichment of single neurons and defined brain regions from human brain tissue samples for subsequent proteome analysis. J Neural Transm. 2015 Jul;122(7):993-1005. doi: 10.1007/s00702-015-1414-4.

10: Nascimento C, Suemoto CK, Rodriguez RD, Alho ATL, Leite REP, Farfel JM, Pasqualucci CA, Jacob-Filho, W, Grinberg LT. Higher prevalence of TDP-43 proteinopathy in cognitively normal Asians: a clinicopathological study on a multiethnic sample. Brain Pathol. 2015 Aug 11. doi: 10.1111/bpa.12296. [Epub ahead of print]

11: Oliveira-Pinto AV, Andrade-Moraes CH, Oliveira LM, Parente-Bruno DR, Santos RM, Coutinho RA, Alho AT, Leite RE, Suemoto CK, Grinberg LT, Pasqualucci CA, Jacob-Filho W, Lent R. Do age and sex impact on the absolute cell numbers of human brain regions? Brain Struct Funct. 2015 Sep 28. [Epub ahead of print]

12: Rodriguez RD, Grinberg LT. Argyrophilic grain disease: an underestimated tauopathy. Dement. Neuropsychol. 2015;9:2-8

13: Seidel K, Mahlke J, Siswanto S, Krüger R, Heinsen H, Auburger G, Bouzrou M, Grinberg LT, Wicht H, Korf HW, den Dunnen W, Rüb U. The Brainstem Pathologies of Parkinson’s Disease and Dementia with Lewy Bodies. Brain Pathol. 2015; 25(2):121-135. PMID: 24995389

14: Stratmann K, Heinsen H, Korf HW, Del Turco D, Ghebremedhin E, Seidel K, Bouzrou M, Grinberg LT, Bohl J, Wharton SB, den Dunnen W, Rüb U. Precortical phase of Alzheimer’s disease (AD)-related tau cytoskeletal pathology. Brain Pathol. 2015 Jul 20. [Epub ahead of print]. PMID: 26193084

15: Theofilas P, Dunlop S, Heinsen H, Grinberg LT. Turning on the Light Within: Subcortical Nuclei of the Isodentritic Core and their Role in Alzheimer’s Disease Pathogenesis. J Alzheimers Dis. 2015 Feb 26 [Epub ahead of print]. PMID: 25720408

16: Ferretti-Rebustini RE, Balbinotti MA, Jacob-Filho W, Rebustini F, Suemoto CK, Pasqualucci CA, Farfel JM, Leite RE, Grinberg LT, Nitrini R. Validity of the Katz Index to assess activities of daily living by informants in neuropathological studies. Rev Esc Enferm USP. 2015 Dec; 49(6):946-52.

1: Corradini BR, Iamashita P, Tampellini E, Farfel JM, Grinberg LT, Moreira-Filho CA. Complex network-driven view of genomic mechanisms underlying Parkinson’s disease: analyses in dorsal motor vagal nucleus, locus coeruleus, and substantia nigra. Biomed Res Int. 2014; 2014:543673. PMID: 25525598

2: Kilimann I, Grothe M, Heinsen H, Alho EJ, Grinberg L, Amaro E, Dos Santos GA, da Silva RE, Mitchell AJ, Frisoni GB, Bokde AL, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Teipel SJ. Subregional Basal forebrain atrophy in Alzheimer’s disease: a multicenter study. J Alzheimers Dis. 2014 Jan 1; 40(3):687-700. PMID: 24503619

3: Oliveira-Pinto AV, Santos RM, Coutinho RA, Oliveira LM, Santos GB, Alho AT, Leite RE, Farfel JM, Suemoto CK, Grinberg LT, Pasqualucci CA, Jacob-Filho W, Lent R. Sexual dimorphism in the human olfactory bulb: females have more neurons and glial cells than males. PLoS One. 2014; 9(11):e111733. PMID: 25372872. PMCID: PMC4221136

4: Schrötter A, Magraoui FE, Gröttrup B, Heinsen H, Marcus K, Meyer HE, Park YM, Grinberg LT. Frontiers in Neurodegeneration – New Insights and Prospects – 20th HUPO BPP Workshop: 15 September 2013, Yokohama, Japan. Proteomics. 2014 Jun; 14(11):1305-7. PMID: 24903697

5: Silva AR, Santos AC, Farfel JM, Grinberg LT, Ferretti RE, Campos AH, Cunha IW, Begnami MD, Rocha RM, Carraro DM, de Bragança Pereira CA, Jacob-Filho W, Brentani H. Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer’s disease. PLoS One. 2014; 9(6):e99897. PMID: 24936870. PMCID: PMC4061071

6: Teipel S, Heinsen H, Amaro E, Grinberg LT, Krause B, Grothe M. Cholinergic basal forebrain atrophy predicts amyloid burden in Alzheimer’s disease. Neurobiol Aging. 2014 Mar; 35(3):482-91. PMID: 24176625

7: Teipel SJ, Flatz W, Ackl N, Grothe M, Kilimann I, Bokde AL, Grinberg L, Amaro E, Kljajevic V, Alho E, Knels C, Ebert A, Heinsen H, Danek A. Brain atrophy in primary progressive aphasia involves the cholinergic basal forebrain and Ayala’s nucleus. Psychiatry Res. 2014 Mar 30; 221(3):187-94. PMID: 24434193

8: Theofilas P, Polichiso L, Wang X, Lima LC, Alho AT, Leite RE, Suemoto CK, Pasqualucci CA, Jacob-Filho W, Heinsen H. A novel approach for integrative studies on neurodegenerative diseases in human brains. J Neurosci Methods. 2014 Apr 15; 226:171-83. PMID: 24503023

9: Villela D, Schlesinger D, Suemoto CK, Grinberg LT, Rosenberg C. A microdeletion in Alzheimer’s disease disrupts NAMPT gene. J Genet. 2014 Aug; 93(2):535-7. PMID: 25189255

1: Andrade-Moraes CH, Oliveira-Pinto AV, Castro-Fonseca E, da Silva CG, Guimarães DM, Szczupak D, Parente-Bruno DR, Carvalho LR, Polichiso L, Gomes BV, Oliveira LM, Rodriguez RD, Leite RE, Ferretti-Rebustini RE, Jacob-Filho W, Pasqualucci CA, Grinberg LT, Lent R. Cell number changes in Alzheimer’s disease relate to dementia, not to plaques and tangles. Brain. 2013 Dec; 136(Pt 12):3738-52. PMID: 24136825

2: Farfel JM, Nitrini R, Suemoto CK, Grinberg LT, Ferretti RE, Leite RE, Tampellini E, Lima L, Farias DS, Neves RC, Rodriguez RD, Menezes PR, Fregni F, Bennett DA, Pasqualucci CA, Jacob Filho W. Very low levels of education and cognitive reserve: A clinicopathologic study. Neurology. 2013 Aug 13; 81(7):650-657. PMID: 23873971

3: Grinberg LT, Nitrini R, Suemoto CK, de Lucena Ferretti-Rebustini RE, Leite RE, Farfel JM, Santos E, Andrade MP, Alho AT, Lima Mdo C, Oliveira KC, Tampellini E, Polichiso L, Santos GB, Rodriguez RD, Ueda K, Pasqualucci CA, Jacob-Filho W. Prevalence of dementia subtypes in a developing country: a clinicopathological study. Clinics (Sao Paulo). 2013; 68(8):1140-5. PMID: 24037011

4: Grinberg LT, Wang X, Wang C, Sohn PD, Theofilas P, Sidhu M, Arevalo JB, Heinsen H, Huang EJ, Rosen H, Miller BL, Gan L, Seeley WW. Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation. Acta Neuropathol. 2013 Apr; 125(4):581-93.

5: Gröttrup B, Esselmann H, May C, Schrötter A, Woitalla D, Heinsen H, Marcus K, Wiltfang J, Meyer HE, Grinberg LT, Park YM. Challenges in Modern Biomarker Discovery – 17(th) HUPO BPP Workshop: May 24-25, 2012, Sao Paulo, Brazil. Proteomics. 2013 Jan; 13(2):210-6.

6: Plum S, Helling S, Theiss C, Leite RE, May C, Jacob-Filho W, Eisenacher M, Kuhlmann K, Meyer HE, Riederer P, Grinberg LT, Gerlach M, Marcus K. Combined enrichment of neuromelanin granules and synaptosomes from human substantia nigra pars compacta tissue for proteomic analysis. J Proteomics. 2013 Dec 6;94:202-6. PMID: 23917253

7: Ribeiro PF, Ventura-Antunes L, Gabi M, Mota B, Grinberg LT, Farfel JM, Ferretti-Rebustini RE, Leite RE, Filho WJ, Herculano-Houzel S. The human cerebral cortex is neither one nor many: neuronal distribution reveals two quantitatively different zones in the gray matter, three in the white matter, and explains local variations in cortical folding. Front Neuroanat. 2013; 7:28. PMID: 24032005

8: Saiki, M.; Leite, R.; Genezini, F.; Grinberg, L.; Ferretti, R.; Farfel, J.; Suemoto, C.; Pasqualucci, C.; Jacob-Filho, W. Trace element concentration differences in regions of human brain by INAA. Journal of Radioanalytical and Nuclear Chemistry 2013; 296 (1), 267-272

9: Schlesinger D, Grinberg LT, Alba JG, Naslavsky MS, Licinio L, Farfel JM, Suemoto CK, de Lucena Ferretti RE, Leite RE, de Andrade MP, Dos Santos AC, Brentani H, Pasqualucci CA, Nitrini R, Jacob-Filho W, Zatz M. African ancestry protects against Alzheimer’s disease-related neuropathology. Mol Psychiatry. 2013 Jan; 18(1):79-85.

10: Suemoto CK, Damico MV, Ferretti RE, Grinberg LT, Farfel JM, Leite RE, Nitrini R, Lafer B, Jacob-Filho W, Pasqualucci CA, Group BA. Depression and cardiovascular risk factors: evidence from a large postmortem sample. Int J Geriatr Psychiatry. 2013 May; 28(5):487-93.’

11: Villela D, Kimura L, Schlesinger D, Gonçalves A, Pearson PL, Suemoto CK, Pasqualucci C, Krepischi AC, Grinberg LT, Rosenberg C. Germline DNA copy number variation in individuals with Argyrophilic grain disease reveals CTNS as a plausible candidate gene. Genet Mol Biol. 2013 Dec; 36(4):498-501. PMID: 24385851

1: de Oliveira KC, Nery FG, Ferreti RE, Lima MC, Cappi C, Machado-Lima A, Polichiso L, Carreira LL, Avila C, Alho AT, Brentani HP, Miguel EC, Heinsen H, Jacob-Filho W, Pasqualucci CA, Lafer B, Grinberg LT. Brazilian psychiatric brain bank: a new contribution tool to network studies. Cell Tissue Bank. 2012 Jun; 13(2):315-26.

2: Grinberg LT, Korczyn AD, Heinsen H. Cerebral amyloid angiopathy impact on endothelium. Exp Gerontol. 2012 Nov; 47(11):838-42.

3: Grinberg LT. Vascular dementia: Current concepts and nomenclature harmonization. Dement. Neuropsychol. 2012;6(3):122-126

4: Korczyn AD, Vakhapova V, Grinberg LT. Vascular dementia. J Neurol Sci. 2012 Nov 15; 322(1-2):2-10.

5: Silva AR, Grinberg LT, Farfel JM, Diniz BS, Lima LA, Silva PJ, Ferretti RE, Rocha RM, Filho WJ, Carraro DM, Brentani H. Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer’s disease. PLoS One. 2012; 7(11):e48751.

6: Thal DR, Grinberg LT, Attems J. Vascular dementia: Different forms of vessel disorders contribute to the development of dementia in the elderly brain. Exp Gerontol. 2012 Nov; 47(11):816-24.

1: Alho EJL, Fonoff ET, Heinsen H, Grinberg LT. Review of printed and electronic stereotactic atlases of the human brain. INTECH Open Access Publisher

2: Ewers M, Frisoni GB, Teipel SJ, Grinberg LT, Amaro E, Heinsen H, Thompson PM, Hampel H. Staging Alzheimer’s disease progression with multimodality neuroimaging. Prog Neurobiol. 2011 Dec; 95(4):535-46.

3: Gigante AD, Young LT, Yatham LN, Andreazza AC, Nery FG, Grinberg LT, Heinsen H, Lafer B. Morphometric post-mortem studies in bipolar disorder: possible association with oxidative stress and apoptosis. Int J Neuropsychopharmacol. 2011 Sep; 14(8):1075-89.

4: Grinberg LT, Rueb U, Heinsen H. Brainstem: neglected locus in neurodegenerative diseases. Front Neurol. 2011; 2:42.

5: Gröttrup B, Böckmann M, Marcus K, Wiltfang J, Grinberg LT, Meyer HE, Park YM. Clinical aspects of neurodegenerative diseases – 15th HUPO BPP Workshop April 8-9, 2011, Bochum, Germany. Proteomics. 2011 Nov; 11(22):4279-83.

6: Gröttrup B, Marcus K, Grinberg LT, Lee SK, Meyer HE, Park YM. Creating a human brain proteome atlas–14th HUPO BPP workshop September 20-21, 2010, Sydney, Australia. Proteomics. 2011 Aug; 11(16):3269-72.

7: Rabinovici GD, Rosen HJ, Alkalay A, Kornak J, Furst AJ, Agarwal N, Mormino EC, O’Neil JP, Janabi M, Karydas A, Growdon ME, Jang JY, Huang EJ, Dearmond SJ, Trojanowski JQ, Grinberg LT, Gorno-Tempini ML, Seeley WW, Miller BL, Jagust WJ. Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD. Neurology. 2011 Dec 6; 77(23):2034-42.

8: Suemoto CK, Nitrini R, Grinberg LT, Ferretti RE, Farfel JM, Leite RE, Menezes PR, Fregni F, Jacob-Filho W, Pasqualucci CA. Atherosclerosis and dementia: a cross-sectional study with pathological analysis of the carotid arteries. Stroke. 2011 Dec; 42(12):3614-5.

9: Teipel SJ, Meindl T, Grinberg L, Grothe M, Cantero JL, Reiser MF, Möller HJ, Heinsen H, Hampel H. The cholinergic system in mild cognitive impairment and Alzheimer’s disease: an in vivo MRI and DTI study. Hum Brain Mapp. 2011 Sep; 32(9):1349-62.

1: Ferretti REL, Damin AE, Brucki SMD, Morillo LS, Perroco TR, Campora F, et al. Post-Mortem diagnosis of dementia by informant interview. Dement. Neuropsychol. 2010;4(2):138-144

2: Ferretti REL, Jacob-Filho W, Grinberg LT, Leite REP, Farfel JM, Suemoto CK, et al. Morphometric brain changes during aging: results from a Brazilian necropsy sample. Dement. Neuropsychol. 2010;4(4):332-337

3: Grinberg LT, Heinsen H. Toward a pathological definition of vascular dementia. J Neurol Sci. 2010 Dec 15; 299(1-2):136-8.

4: Grinberg LT, Rueb U, Alho AT, Heinsen H. Brainstem pathology and non-motor symptoms in PD. J Neurol Sci. 2010 Feb 15; 289(1-2):81-8.

5: Grinberg LT, Thal DR. Vascular pathology in the aged human brain. Acta Neuropathol. 2010 Mar; 119(3):277-90.

1: Azevedo FA, Carvalho LR, Grinberg LT, Farfel JM, Ferretti RE, Leite RE, Jacob Filho W, Lent R, Herculano-Houzel S. Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain. J Comp Neurol. 2009 Apr 10; 513(5):532-41.

2: Grinberg LT, Amaro Junior E, da Silva AV, da Silva RE, Sato JR, dos Santos DD, de Paula Pacheco S, de Lucena Ferretti RE, Paraizo Leite RE, Pasqualucci CA, Teipel SJ, Flatz WH. Improved detection of incipient vascular changes by a biotechnological platform combining post mortem MRI in situ with neuropathology. J Neurol Sci. 2009 Aug 15; 283(1-2):2-8.

3: Grinberg LT, Rüb U, Ferretti RE, Nitrini R, Farfel JM, Polichiso L, Gierga K, Jacob-Filho W, Heinsen H. The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer’s disease. A precocious onset? Neuropathol Appl Neurobiol. 2009 Aug; 35(4):406-16.

4: Grinberg, L.T and Heinsen, H. Argyrophilic grain disease: an update about a frequent cause of dementia. Dementia & Neuropsychol. 2009;3:2-7

5: Paula-Lima AC, Tricerri MA, Brito-Moreira J, Bomfim TR, Oliveira FF, Magdesian MH, Grinberg LT, Panizzutti R, Ferreira ST. Human apolipoprotein A-I binds amyloid-beta and prevents Abeta-induced neurotoxicity. Int J Biochem Cell Biol. 2009 Jun; 41(6):1361-70.

6: Suemoto C.K, Ferretti, R.E.L, Grinberg, L.T, Oliveira, K.C, Farfel, J.M, Leite, R.E.P, Ricardo Nitrini, Jacob-Filho W, Pasqualucci, C.A, Brazilian Aging Brain Study Group. Association between cardiovascular disease and dementia. Dementia & Neuropsychol. 2009; 3:308-314

7: Takada L.T, Camiz P, Grinberg L.T, Leite, C.C.. Non-inflammatory cerebral amyloid angiopathy as a cause of rapidly progressive dementia: A case study. Dementia & Neuropsychol. 2009;3:352-357

1: Grinberg LT, Amaro E, Teipel S, dos Santos DD, Pasqualucci CA, Leite RE, Camargo CR, Gonçalves JA, Sanches AG, Santana M, Ferretti RE, Jacob-Filho W, Nitrini R, Heinsen H. Assessment of factors that confound MRI and neuropathological correlation of human postmortem brain tissue. Cell Tissue Bank. 2008 Sep; 9(3):195-203.

2: Grinberg LT, Ferraz da Silva LF, Galtarossa Xavier AC, Nascimento Saldiva PH, Mauad T. Clinico-pathological discrepancies in the diagnoses of solid malignancies. Pathol Res Pract. 2008; 204(12):867-73.

3: Leite, R.E.P; Jacob Filho, W.; Saiki, M.;Grinberg, L.T, Ferretti, R.E.L. Determination of trace elements in human brain tissues using neutron activation analysis. J Radioanal Nucl Chem 2008;278: 581-584

4: Ravid R, Grinberg LT. How to run a brain bank–revisited. Cell Tissue Bank. 2008 Sep; 9(3):149-50.

5: Teipel SJ, Meindl T, Grinberg L, Heinsen H, Hampel H. Novel MRI techniques in the assessment of dementia. Eur J Nucl Med Mol Imaging. 2008 Mar; 35 Suppl 1:S58-69.

1: Grinberg LT, Ferretti RE, Farfel JM, Leite R, Pasqualucci CA, Rosemberg S, Nitrini R, Saldiva PH, Filho WJ. Brain bank of the Brazilian aging brain study group – a milestone reached and more than 1,600 collected brains. Cell Tissue Bank. 2007; 8(2):151-62.

2: Grinberg, L.T and Heinsen, H. Computer-assisted 3D reconstruction of the human basal forebrain complex. Dementia & Neuropsychol. 2007,2:140-146

3: Grinberg, L.T, Ferretti, R.E.L ,Leite, R.E.P, Farfel, J.M, Pacheco, S.P , Alho A.T.L, Grisoli, R.P, Matos, H.T.M, Moreira, E.G, Balbino, E, Oliveira, K.C, Rosemberg,S, Carvalho, H.B, Pasqualucci, C.A, Saldiva, P.H.N, Jacob-Filho W , Nitrini, R, and Brazilian Aging Brain Study Group. Clinicopathological correlates of Alzheimer’s disease in a general autopsy series from Brazil. Dementia & Neuropsychol. 2007,4:356-360